Monday, April 27, 2015

Acute myocardial infarction

Introduction
The acute myocardial infarction occurs when the flow of blood to the heart is blocked, most often by a build-up of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). The interrupted blood flow (oxygen supply) can damage or destroy part of the heart muscle. a portion of the heart is starved of oxygen, a condition called "cardiac ischemia." If cardiac ischemia lasts too long, the starved heart tissue dies. This is called as heart attack also known as a myocardial infarction.


Presentation
Signs & symptoms
·         Pressure, tightness, pain, or a squeezing or aching sensation in the chest or arms that may spread to the neck, jaw or back
·         Nausea, indigestion, heartburn or abdominal pain
·         Shortness of breath
·         Cold sweat
·         Fatigue
·         Lightheadedness or sudden dizziness (Mayoclinicorg, 2015)

Causes
coronary artery diseases, coronary artery can narrow from the buildup of various substances, including cholesterol (atherosclerosis)
During a heart attack, one of these plaques can rupture and spill cholesterol and other substances into the bloodstream. A blood clot forms at the site of the rupture. If large enough, the clot can completely block the flow of blood through the coronary artery.
A spasm of a coronary artery that shuts down blood flow to part of the heart muscle.

Risk factors
·         Age. Men age 45 or older and women age 55 or older are more likely to have a heart attack than are younger men and women.
·         Tobacco. Smoking 
·         High blood pressure
·         High blood cholesterol or triglyceride levels. A high level of low-density lipo protein (LDL) and high level of triglycerides.
·         Diabetes
·         Family history of heart attack.
·         Lack of physical activity.
·         Obesity
·         Stress
        A history of pre clampsia. This condition causes high blood pressure during pregnancy and increases the lifetime risk of heart disease.
·         A history of an autoimmune condition (Colin 2012).  

Test and diagnosis
·         Electrocardiogram (ECG)
·         Blood tests. Certain heart enzymes slowly leak out into the blood stream while heart has been damaged by a heart attack.

Additional tests
·         Chest X-ray. (To check the size of heart and its blood vessels and to look for fluid in lungs)
·         Echocardiogram
·         Coronary catheterization (angiogram)
·         Exercise stress test. Stress tests measure how your heart and blood vessels respond to exertion.
·         Cardiac computerized tomography (CT) or magnetic resonance imaging (MRI)

Management 
*Aspirin, it reduces blood clotting, thus helping maintain blood flow through a narrowed artery.
*Thrombolytic, help dissolve a blood clot that's blocking blood flow to heart.
*Antiplatelet agents. These include medications, such as clopidogrel (Plavix) and others, called platelet aggregation inhibitors.
*Other blood-thinning medications, such as heparin
*Pain reliever, such as morphine
* Nitroglycerin. This medication, used to treat chest pain (angina), can help improve blood flow to the heart by widening (dilating) the blood vessels. (Uptodate 2015).
*Beta blockers. These medications help relax heart muscle, slow heart rate and decrease blood pressure and also can limit the amount of heart muscle damage and prevent future heart attacks.
* ACE inhibitors. These drugs lower blood pressure and reduce stress on the heart.
And cholesterol lowering medications. 
Surgical and other procedures
*Coronary angioplasty and stenting
*Coronary artery bypass surgery

*Life style modifications such as, avoid smoke, avoid alcohol, control blood pressure and cholesterol levels, get regular medical checkups, exercise regularly, maintain a healthy weight, eat a heart-healthy diet, manage diabetes and control stress.
(NICE 2015). 

References

Reeder S,Harold L K (2015). Criteria for the diagnosis of acute myocardial infarction. [ONLINE] Available at: http://www.uptodate.com/contents/criteria-for-the-diagnosis-of-acute-myocardial-infarction. [Last Accessed 20 april 2015

Colin, T 2012, 'Acute Myocardial Infarction', retrieved 16th of March 2015, <http://www.patient.co.uk/doctor/acute-myocardial-infarction>

Mayoclinicorg. 2015. Mayoclinicorg. [Online]. [6 May 2015]. Available from: http://www.mayoclinic.org/diseases-conditions/heart-attack/basics/definition/con-20019520




No comments:

Post a Comment